Volume 11, Issue 2 (10-2019)                   2019, 11(2): 8-16 | Back to browse issues page


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Pahlavani N, Sadeghi O, Ebrahimi F, Mazloumi Kiapey S S, Nurany M. The Effects of l-arginine Supplementation on Athletic Performance and Risk Factors of Cardiovascular Disease: Review of Current Evidence. North Khorasan University of Medical Sciences 2019; 11 (2) :8-16
URL: http://journal.nkums.ac.ir/article-1-1817-en.html
1- Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , pahlavaniN951@mums.ac.ir
2- Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
3- Department of Nutrition, School of Health, Iran University of Medical Sciences, Tehran, Iran
4- Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5- School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
Abstract:   (5271 Views)
Introduction: Due to controversies in different studies about the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors, this study aimed to review the current evidence on the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors.
Methods: This study was done to summarize findings from earlier evidence on the effect of L-arginine supplementation on the risk of cardiovascular disease. We searched in PubMed, Scopus and Google Scholar through 1975 till 2017 using the following keywords: cardiovascular OR athletic performance OR hypertension OR blood pressure OR sports performance OR lipid profile in combination with L-arginine OR arginine. After reviewing title and abstracts, all clinical trials and cross-sectional studies conducted on healthy people or those suffering from the disease were included.
Results: In most studies, consumption of L-arginine supplementation improves athletic performance and body composition in athletes, although there are some contradictions in this field. Most studies confirmed the effect of L-arginine on decrease cardiovascular risk factors, and most of the work considered that this effects as a result of increased levels of nitric oxide (NO) in serum.
Conclusions: Most of the clinical trials indicated favorable effects of L-arginine supplementation on athletic performance and cardiovascular risk factors and taking this supplement at a dose of 2-5 grams per day has no side effects and promotes the health. Due to controversies in some study for giving high doses of this s
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Type of Study: Review Article | Subject: Basic Sciences
Received: 2018/11/5 | Accepted: 2019/01/30 | Published: 2019/10/5

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