Journal of North Khorasan

Background & Objectives: Depression is one of the most popular psychological disorders. There are various methods of treatment on it. This study aimed to assess the efficacy of meta-cognitive therapy in reducing depressive symptoms and improving quality of life in patients with MDD has been conducted. Methods and materials: The design was an experimental with pre and post-test and control group. Sampling method was available sampling. The 22 female subjects were evaluated by the psychiatrist for choosing according to DSM-V. Then subjects were put in one of two groups experimental and control. The experimental group was studied for two months. BDI-II and WHOQOL-BREF were given to the subjects before and after treatment and at the 3 month follow up period. The results were analyzed using mixed analysis of variance. Results: The results showed that meta-cognitive therapy, significantly reduced depressive symptoms (p<0/001) and increased quality of life (p<0/001) in the experimental group in the post-test and follow-up phase. Conclusion: metacognitive therapy created significant changes to reduce depressive symptoms and improve the life quality of depressed patient. This result is interpretable in the context of the third wave of behavioral perspective. It seems that this therapy is effective in reducing depressive symptoms and improving life quality of these patients, therefore it is recommended as an effective therapy for major depression.