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JNKUMS 2017, 9(2): 193-202 Back to browse issues page
Acute effect of endurance training on amyloid A and oxidized LDL levels in obese men
J Mehrabani *1, T SaeidiZiabari, F Mehrabani, A Jorbonian
1- , mehrabanij@gmail.com
Abstract:   (62 Views)
Background & objectives: Obesity and inflammatory markers such as amyloid A (SAA) and oxidized LDL (Ox-LDL) are the leading causes of cardiovascular diseases. Physical activity has a positive effect in reducing the risk factors of these diseases. The aim of present study was to investigate the role of one session endurance exercise on cycle ergometer on serum amyloid A and Ox-LDL in the obese and normal weight young men.
Material and Methods: Twenty two male students were participated and divided into two groups: normal weight (n=12; mean±SD of age 25.12±1.42 yrs, weight 69.91±2.75 kg and height 173.04±2.75 cm) and obese (n=10; age 26.45±1.39 yrs, weight 91.15±7.40 kg and height 173.6±3.6 cm). The exercise protocol involved one session pedaling exercise on cycle ergometer with the intensity of 65% of VO2max for 60 minutes. Blood samples were gathered before and after completion of the exercise protocol. SAA and Ox-LDL levels were measured by ELISA method.
Results: The U Man Whitney test showed that the Ox-LDL levels in obese group were higher than that in the normal weight group after exercise (P≤0.05). In obese group, levels of SAA were higher than that in the normal weight group after exercise (P≤0.05). Paired t test showed SAA levels in both groups were significantly increased in comparison with the pre-exercise (P≤0.05). In both groups, a significant correlation was found between SAA and BMI, and in the obese group between Ox-LDL and BMI (P≤0.05).
Conclusions: A single bout endurance exercise increased the levels of SAA and OX-LDL, and it seems that these changes affect higher body mass and exercise-induced acute inflammation.
Keywords: obesity, endurance exercise, acute inflammatory response, amyloid A, oxidized LDL
Full-Text [PDF 262 kb]   (54 Downloads)    
Type of Study: Orginal Research | Subject: Basic Sciences
Received: 2017/09/23 | Accepted: 2017/09/23 | Published: 2017/09/23
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DOI: 10.18869/acadpub.jnkums.9.2.193


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Mehrabani J, SaeidiZiabari T, Mehrabani F, Jorbonian A. Acute effect of endurance training on amyloid A and oxidized LDL levels in obese men . JNKUMS. 2017; 9 (2) :193-202
URL: http://journal.nkums.ac.ir/article-1-1199-en.html
Volume 9, Number 2 (10-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی خراسان شمالی Journal of North Khorasan University of Medical Sciences
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