Journal of North Khorasan

Abstract Introduction:Heavy water (high solute concentration water) has been proposed as important risk factor in areas that have reserves of heavy water. The aim of this study is to determine the main cause of stone forming in Shahrod area, which is of heavy water reserved. Material and methods 100 patients with urinary stone in Shahrod city were studied. History and physical exam, stone component test, blood test of complete blood count, calcium, phosphate, urate and simple urine test accurately infection, ph, crystal, and cystine were examined in all patients. 24 hour urine test in order to determine risk factors of stone forming were performed in individuals with a history of stone their family, previous stone or multiple stone. Results:Low water intake that defined as less than 2liters urination in 24hour observed in 81 patients (81%).Low level of citrate were found in 32 patients (32%).In 11 patients (11%) ) other causes of stone forming like hypercaliuria were observed. Conclusion:Low water intake and low level of citrate in normal diet of Shahrod city people are the main cause of stone forming in people of this area.Heavy water and hypercalciuria had no significant role in stone forming in this area.