Journal of North Khorasan

Abstract Background & objectives: Hepatitis B is a viral disease with high prevalence .Vaccination of at risk persons like medical students will preven of infection. Unfortunately immunologic response to the vaccines is not perfect sometimes and it is necessary to examine the immune response. Materials &Methods: In a cross-sectional study of 210 female students that have been vaccinated against hepatitis B at the dormitories of North Khorasan University of Medical Sciences ,Bojnurd in 2013. After collecting demographic data , sampling of blood was done and antibody titer HBV was assessed by ELISA. Data were analyzed by SPSS software and presented with chi-square test. Results : Among 210 participants, 198 completed the 3 stages of vaccination against HBV and 91.9 % of participating in the study had adequate response against hepatitis. Also, there were no significant correlation between the immunity response, diabetes, family history, living in urban or rural and marriage condition. Conclusion: In this study immunity against hepatitis was in acceptable level. Health education and evaluation of immune responses against hepatitis in medical staff and students is very effective. Also revaccination for persons with low titers of antibody is essential.