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2008, 1(1): 13-20 |
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Rezaiyan A, Irvani M, Amiri M, Reyhani S. Clinical and Para clinical findings and initial treatment response of children with leishmaniasisa dmitted in Imam Reza Hospital from 2000 to 2008 in Bojnurd, Iran. North Khorasan University of Medical Sciences 2008; 1 (1) :13-20
URL: http://journal.nkums.ac.ir/article-1-425-en.html
URL: http://journal.nkums.ac.ir/article-1-425-en.html
1- , rezaiyan-saba @yahoo.com
Abstract: (4145 Views)
Background:
Visceral Leishmaniasis(VL) is a spreading potentially fatal zoonosis in Iran mimicking many other
diseases in infancy which differs from VL in some other regions in terms of it’s clinical characteristics and response totherapy; earlier and better management is quite effective for life saving.So we tried to look at our cases from demographic,clinical and also initial response to therapy in a tertiary,educational center in Bojnurd, Iran.
Patients and Methods:
30 cases with final diagnosis of VL,who were discharged from Imam Reza hospital from 2000 to 2008 were enrolled in this descriptive-analytic retrospective study; demographic,clinical,paraclinical parameters as well data concerning initial response to treatment were gathered and analyzed by appropriate statistical methods by SPSS software.
Results:
Fever was the mostcommon symptom and observed in allcasesfollowed by splenomegaly,hepatomegaly,pallor, weight loss and cough. Paraclinical findingswere anemia, thrombocytopenia,leukopenia,lymphocytosis, increase of ESR and CRP.
Conclusion:
Clinical symptoms, paraneoplastic symptoms, weight loss and fever were the most prominentfinding in patients with visceral leishmaniasis.There was a significant rate of mortality in this region and follow up studies are needed.
Visceral Leishmaniasis(VL) is a spreading potentially fatal zoonosis in Iran mimicking many other
diseases in infancy which differs from VL in some other regions in terms of it’s clinical characteristics and response totherapy; earlier and better management is quite effective for life saving.So we tried to look at our cases from demographic,clinical and also initial response to therapy in a tertiary,educational center in Bojnurd, Iran.
Patients and Methods:
30 cases with final diagnosis of VL,who were discharged from Imam Reza hospital from 2000 to 2008 were enrolled in this descriptive-analytic retrospective study; demographic,clinical,paraclinical parameters as well data concerning initial response to treatment were gathered and analyzed by appropriate statistical methods by SPSS software.
Results:
Fever was the mostcommon symptom and observed in allcasesfollowed by splenomegaly,hepatomegaly,pallor, weight loss and cough. Paraclinical findingswere anemia, thrombocytopenia,leukopenia,lymphocytosis, increase of ESR and CRP.
Conclusion:
Clinical symptoms, paraneoplastic symptoms, weight loss and fever were the most prominentfinding in patients with visceral leishmaniasis.There was a significant rate of mortality in this region and follow up studies are needed.
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2015/03/28 | Accepted: 2015/03/28 | Published: 2015/03/28
Received: 2015/03/28 | Accepted: 2015/03/28 | Published: 2015/03/28
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