Background & Objectives:NovaMin is a synthetic mineral composed of calcium, sodium, phosphorous and silica releases deposites of crystalline hydroxyl-carbonate apatite similar to tooth mineral composition. Furthermore, hydroxyapatite is a well known material for the remineralization of tooth enamel surface. The present study compared the efficacy of NovaMin and Nano-hydroxyapatite in the remineralization of carious lesions in permanent teeth. Materials and Methods:In an experimental in vitro trial, 30 impacted third molars teeth without any crack were selected and artificial carious lesions were developed on the teeth after exposing to demineralization / remineralizion cycles. The teeth were randomly treated with a NovaMin-contained dentifrice or nano-hydroxyapatite 2 minutes daily for a total 5 days and their Vicker’s microhardness values were calculated. The data were subjected to Student T and Mann-whitney U tests. Result: The SMH was found to be higher in the teeth treated with NovaMin toothpaste (412.87kgf/mm2) than that in the teeth treated with NHA (388.40 kgf/mm2) however, this difference was not statistically significant. Conclusion:Both NovaMin-contained dentifrice and Nanohydroxyapatite solutions were effective to increase remineralization of carious-like lesions in permanent teeth.
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