Abstract Background & Objectives: Sensory deprivation is one of the complications threatening the comatose patients. Sensory stimulation is a treatment that awakes the brain's reticular activating system, which helps brain re-organization. This study aimed to investigate the impact of familiar sensory stimulation on level of Consciousness in patients with head injury in ICU. Material & Methods: This clinical trial was conducted on 60 patients with head injury in ICUs of Mashhad Emdadi Hospital. Intervention was the presence of family members and provides sensory stimulation in first 6 days of admission. Patients consciousness checked on GCS score on the first day and sixth and findings was analyzed with the SPSS 11.5. Results: According to the non-normal distribution of the GCS, the Mann-Whitney test was used. The results of this test showed that the GCS in first day were homogeneous in two groups (P=0/402). Increase of GCS on the sixth day in the intervention group was more statistically significant than the control group (P=0/002). Conclusion: Early sensory stimulation is increase consciences in patients with brain injury. Revising in visiting policy in intensive care unit can be appropriate to provide positive effects of family presence on patient.