Journal of North Khorasan

Abstract Background and Aims:Propofol is the first line drug for intravenous induction of anesthesia. Short action duration and few adverse effects along with potent antiemetic properties made it the most widely used drug Spontaneous movement or myoclonus is one of its adverse effects. We aimed to study the incidence, time of onset, quantity, and quality of the myoclonus and its related factors. Material and methods:The study was conducted on 204 patients who received Propofol for induction while observed by two anesthesiologists for detecting myoclonus. All patients were monitored for depth of anesthesia according to Bispectral index. The abnormal movement was recorded according to movement score. To find the relationship between myoclonus and other variables, logistic regression was applied. All analysis were done using software SPSS version 16. Results:60 patients out of 204 developed myoclonus corresponding with an incidence of 29%. The mean weight in these patients was significantly lower than the patients without myoclonus and they received higher dose of Propofol per kilogram of body weight. Multivariate logistic regression corroborates the relation of age and dose with the incidence of myoclonus. Conclusion:Comparing this study with other studies, a hypothesis about the impact of race on the dose of Propofol required to achieve the planned level of anesthesia is figured out. The difference in dose requirement between races and the importance for prevention of myoclonus remains to be studied in large multicentre studies.

Abstract Background and Objectives: Life style is composed of a chain of active parameters in all dimensions of human life and has a substantial impression on health of population. Since vast majority of health problems has a strong relationship to life style, occurrence of many somatic and psychological disorders would be prevented provided that life style rectified. Blood pressure is one of the most important health criteria moderated when life style has been changed. The aim of this investigation was to study the cause_ effect relationship of life style and blood pressure in administrative employees in Bojnurd rural areas. Materials and Methods: In this descriptive-analytical (cross sectional) study 380 cases of governmental administrative employees were selected on a stratified random sampling with proportional allocation basis. The Study was conducted on 2012 in Bojnourd city of Iran. Primary data gathering tools were data recording sheet and lifestyle questionnaire. BP ≥ 90/140 were considered as hypertensive. The data analyzed in SPSS software. (V18) Results: The life style in 3 levels of desirable ,relatively desirable and undesirable estimated to be 4.58, 52.48 and 42.94 respectively. 7.4% of those studied suffered from high systolic blood pressure and 15.2% had diastolic hypertension. Blood pressure was significantly related to age, weight, height, marital status, exercise, nutrition, stress and body mass index. Conclusions: stress, malnutrition and obesity are among the factors influencing the incidence of hypertension. The essence of implementation of ongoing intervention programs by official bodies to change individual behaviors and lifestyle seems to be required.