Showing 4 results for Seifi
H Hosseinkazemi , T Molania , H Abbaszadeh , S Seifi , Sh Zahedpasha ,
Volume 8, Issue 1 (6-2016)
Abstract
Peripheral Ameloblastoma (PA) is a rare extraosseous counterpart of central ameloblastoma that occures in soft tissuses and may cause bone crest resorption.the most frequent onset site is the mandibular premolar region especially the lingual gingiva. The incidence of peripheral ameloblastoma in the sixth decade of life and the prevalence have been reported in men than in women. Peripheral ameloblastoma compared to the intraosseous type later in life happens. we report a case of peripheral aneloblastoma in the maxillary gingiva in a 28-year-old woman.
Keyword:peripheralameloblastoma,gingivalleasion,odontogenic tumor
Farnaz Seifi-Skishahr, Maghsoud Nabilpour,
Volume 14, Issue 3 (11-2022)
Abstract
Introduction: Research efforts for early prediction of COVID-19 are still ongoing. This study aimed to introduce an index for predicting lung involvement in hypertensive patients with COVID-19.
Method: All hypertensive patients with COVID-19 who were hospitalized in the intensive care unit of Imam Sajjad Hospital in Tabriz, Iran, from February 1400 to May 1401 comprised the statistical population of this study, who were selected as the statistical sample by the census. The vitamin D concentration, C-reactive protein, and L-cysteine levels in serum were determined by the ELISA technique. An independent t-test was used to analyze the differences between groups. In addition, the C-reactive protein to L-cysteine ratio was calculated in both groups. A P-value of less than 0.05 was considered statistically significant.
Results: All hypertensive patients with COVID-19 admitted to the intensive care unit had lung involvement of > 50% and vitamin D deficiency of < 20 ng/ml. The Vitamin D concentration was > 26 ng/ml in healthy individuals. The findings showed hypertensive patients with COVID-19 had significantly higher levels of C-reactive protein, L-cysteine, and C-reactive protein to L-cysteine ratio than healthy individuals (P≤0.005).
Conclusion: The ratio of C-reactive protein to L-cysteine and vitamin D deficiency could better predict lung involvement in hypertensive patients with COVID-19
Maghsoud Nabilpour, Farnaz Seifi, Ameneh Pour Rahim,
Volume 15, Issue 4 (winter 2024)
Abstract
Introduction: Sports activity increases the expression of PGC-1α, the regulatory factor of mitochondrial biogenesis. This study aimed to investigate the effect of eight weeks of Moderate-intensity Continuous Training (MICT) and High-intensity Intermittent Training (HIIT), along with sodium citrate supplementation, on PGC-1α expression in male Wistar rats.
Method: Forty rats were placed in the following five groups: Control, MICT, MICT+sodium citrate, HIIT, and HIIT+sodium citrate. The continuous training group ran for eight weeks and five sessions per week with an average intensity of 70% of the maximum running speed for 15-30 minutes. The interval training group ran for 12 minutes with an intensity range of 50% and 90%. In addition to exercise, the exercise+supplement groups received 15 mmol/l sodium citrate supplement daily. The expression of PGC-1α in the soleus muscle was measured by the western blot method. Data analysis was done using one-way analysis of variance and Tukey's post hoc test.
Results: The PGC-1α protein expression increased in both the training groups and the training+supplement groups compared to the control group (P=0.001). Furthermore, adding sodium citrate could significantly increase the PGC-1α expression in the MICTgroup+supplement compared to the MICT group (P=0.005). However, the HIIT had a higher effect on PGC-1α expression than the MICT group.
Conclusion: Despite the effectiveness of both training methods, sodium citrate supplementation before HIIT could have more synergistic effects in increasing the expression of PGC-1α.
Sajjad Ramezani, Farnaz Seifi – Skishahr,
Volume 16, Issue 2 (Summer 2024)
Abstract
Introduction: Aging process with progressive decrease of cardiac function is due to the death of cardiac myocyte characterized by apoptosis. On the other hand, physical activity not only improves heart function, but also reduces the risk of heart disease. Therefore, the aim of this study was to investigate the effect of 8 weeks of continuous moderate exercise on BAX, P53, and caspase 3 gene expression in the heart tissue of aged male rats.
Method: In this experimental study, 16 male Wistar rats with an average age of 19±2.25 months and weight of 350.02±20.12 grams were randomly divided into two groups of moderate intensity continuous training (MT) and control (C). The continuous aerobic exercise program (MICT) was performed for 8 weeks and five sessions per week with an intensity of 60-75% of the maximum speed. Then, 48 hours after the last exercise session, heart tissue was removed under general anesthesia. BAX, P53, and caspase 3 gene expression values were measured by real time PCR method. Independent t statistical method was used in SPSS 21 software for data analysis.
Results: The results showed that performing eight weeks of moderate-intensity continuous training caused a significant decrease in the apoptotic indices of BAX (P=0.012), P53 (P=0.015), and caspase 3 (P=0.002) in the heart tissue of elderly rats compared to the control group.
Conclusion: It seems that regular aerobic exercises with moderate intensity can significantly reduce the apoptosis index of heart tissue and the aging process.
