Showing 6 results for Essential Oil
F Yarahmadi , A Rajabpour , N Zandi Sohani, L Ramezani ,
Volume 4, Issue 5 (3-2013)
Abstract
Abstract Background & Objectives:Plant essential oils are pest control tools that have good prospect with attention to rich plant flora of Iran. Material and Methods:For first time in the world, repellency effects of Geranium, Pelargonium roseum Andrews, Galbanum, Ferula gumosa Boiss., and Artemisia, Artemisia sieberi Besser, essential oils on adults of Bemisia tabaci Gen. (Hom., Aleyrodidae) were evaluated by choice test under laboratory condition. Results:Result showed that landed adults on treated leaves by 12 ppm of each essential oil were significantly lower than control treatment. Conclusion:This data implicated suitable protective effects of the essential oils to the pest infestation. Thus, essential oils distillated from Geranium, Artemisia and Galbanum could be applied to control B. tabaci in greenhouse cucumber at V/V 12ppm
A Arianfar , M Mehraban Sang Atash , S Salhe Abadi ,
Volume 9, Issue 1 (7-2017)
Abstract
Background & Objectives: Madder perennial herb or Rubia florida is an industrial plant which is mainly used as a dye in the past time. The purpose of this study was to investigate the essential active compounds in Rubia florida oil. That is native in North Khorasan province and this project paves the way for future pharmaceutical researches and applications.
Materials and Methods: Samples were collected and extracted by water distillation method after drying at room temperature. The essential oils yield was %0.031. Components of essential oil were studied with gas chromatography mass spectrometer (GC/MS). Identification of essential oil components was done using a gas chromatography which was connected to a mass spectrometer GC- MASS. Identification of essential constituent compounds was done using the retention indices and mass spectra of compounds and comparing them with standard mass spectra in the computer libraries.
Results: The yields of aerial parts of Rubia florida was 031.0% and 32 compound were identified in essential oil. The major compounds such as Decane (8.38%), Palmitic acid (8.07%), octane (% 6.55), Palmitic acid methyl ester (% 5.11), linoleic acid, ethyl esther (% 5.53) were identified in the essential oil.
Conclusion: Researchers demonstrated the antioxidant and anti-cancer activity and prevention of food allergy in the cis and trans isomers of linoleic acid. Due to the composition it was concluded that the 52.12% of extracts of Rubia florida had antioxidant compounds.
Sara Firuzeh, Parastoo Zarghami Moghaddam, Ameneh Mohammadi, Asma Asad Nejad, Mahsa Taheri Bazkhaneh, Jamal Kasaian, Peiman Alesheikh,
Volume 12, Issue 1 (6-2020)
Abstract
Introduction: With increasing resistance to overuse of synthetic chemical antibiotics, it is necessary to find alternative drugs that have both antibacterial and minimal side effects. The aim of this research is the effect of different types of solvents on the extraction of effective antibacterial agents of the plant and the identification of chemical compounds of Arenaria hispanica essential oil in North Khorasan province. Methods: Arenaria hispanica with locally name ‘Marjaneh’, after collection and drying, was extracted using various solvents by maceration method. Essential oil distillation was performed by Clevenger apparatus and the compounds were analyzed by gas chromatography-coupled mass spectrometry (GC/MS). Disk and well diffusion method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were used to determine the antibacterial activity.
Results: The extracts had effect only on gram positive bacteria and the inhibitory effects of methanolic extract was more than others. Escherichia coli was the most resistant and Bacillus cereus was the most susceptible bacterium, which showed no statistically significant differences between groups (P > 0.05). The MIC / MBC results showed that none of the extracts were able to inhibit or remove the bacteria and higher concentrations are required. Nonadecane was the main compound identified in the essential oil.
Conclusions: Different extracts had less antibacterial effects than commercial antibiotics and small numbers of compounds were identified by the GC/MS analysis.
Hadi Yazdani, Amir Amani, Maryam Besharati, Maryam Tatari, Ali Marjani,
Volume 14, Issue 3 (11-2022)
Abstract
Introduction: Medicinal plants have played a major role in the treatment of multiple diseases for centuries. Ziziphora clinopodioides is one of these plants with well-known antibacterial properties. The present study aimed to investigate the antibacterial effects of Z. Clinopodioides essential oil and nanoemulsion.
Method: After preparing and collecting the plant in spring, the samples were dried in the shade and transferred to the laboratory. Thereafter, the essential oil was extracted by Clevenger. Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus were used to determine antibacterial properties.
Results: Pulegone had the highest composition (44.49%) of essential oil. Particle size in 5% nanoemulsion of Z. Clinopodioides essential oil was 13.0 nm. The results demonstrated that considering the diameter zone of the no-growth, there was no significant difference between 5% nanoemulsion and 5% Z. Clinopodioides essential oil in both gram-positive and gram-negative bacteria.
Conclusion: Nanoemulsion containing essential oil showed no significant difference in antibacterial activity compared to essential oils
Elyas Salahi, Ahmad Asgharzadeh, Amir Amani, Maryam Besharati, Maryam Tatari,
Volume 15, Issue 1 (5-2023)
Abstract
Introduction: The Artemisia plant is known by its scientific name, which is the exclusive species of Kopeh Daghi in Iran. The present study aimed to design a nanoemulsion of the essential oil of Kopeh Daghi and investigate its antimicrobial activity on the gram-negative bacteria Escherichia coli and the gram-positive bacteria Staphylococcus aureus.
Method: At first, the essential oil extraction was performed using a Clevenger. Nanoemulsion was prepared by a spontaneous method using Tween 80 as oil in water. The size of nanoparticles was determined using the dynamic light scattering method. The antioxidant and antibacterial effects of Nanoemulsion at a concentration of 15% of essential oil were investigated.
Results: In the current research, 38 compounds were identified in the species of Artemisia kopetdaghensis, of which Davanone, with 28.89%, was the most effective substance. The results of the antioxidant test demonstrated that pure essential oil (IC₅₀= 7.05 mg/ml) and Nanoemulsion containing essential oil (IC₅₀= 46.51 mg/ml) had the highest antioxidant activity, respectively. Furthermore, regarding the inhibition of bacterial growth, Nanoemulsion was the most effective in Staphylococcus aureus with a non-growth zone diameter of 8 mm. In Escherichia coli, pure essential oil was the most effective, with a non-growth zone diameter of 9 mm.
Conclusion: In general, the antibacterial properties of 15% nanoemulsion were better compared to 15% essential oil. Moreover, Nanoemulsion containing the medicinal plant essential oil had more antioxidant properties compared to 15% essential oil
Shidrokh Abootorabi, Zahra Kardan,
Volume 16, Issue 3 (9-2024)
Abstract
Introduction: Studies have pointef to anti-inflammatory properties of atorvastatin. In this research, noisome nanoparticles have been used to increase skin penetration and drug retention.
Method: Atorvastatin niosomes were prepared using the sonication method. The effect of cholesterol: surfactant mixture ratio was investigated on physicochemical properties of nanoparticles. Studies have been performed on the morphological features, and characterization of nanoparticles. The toxicity of optimal formulation was investigated on a normal human fibroblast cell line. Different percentages of lavender essential oil were added to the optimal formulation gel, and skin drug delivery studies were performed.
Results: The optimal formulation had the optimum particle size, PDI, zeta potential, and EE%, which leads to higher stability and dissolution of atorvastatin in the body. Morphological studies conducted on properties of nanoparticles illustrated a spherical shape and no interference with other formulation components. No cytotoxicity was detected for improved formulation of nanoparticles, including atorvastatin. In-vitro skin permeation results indicated that gel containing 0.5% lavender essential oil atorvastatin noisome (Atrosome) could enhance the dermal delivery of atorvastatin where a higher concentration of atorvastatin can be detected in skin layers.
Conclusion: As evidenced by the results of this study, preparing nanoparticles from atorvastatin and adding essential oil to the final formulation exerts a positive effect on local drug delivery. Moreover, drug delivery with nanocarriers significantly increased the percentage of drug retention in the target site.
