Journal of North Khorasan

Abstract Background & Objective: Incidence and prevalence of cancer is increasing worldwide, especially in the low and middle income countries, including I.R o Iran. Valid data is needed to measure burden of cancer and take appropriate decision towards cancer control. Due to limitation of cancer registrations it is hard to make an inference about cancer in Itan. It is important to measure how complete and valid is the report of cancer incidence and mortality. Material & Method: We prepared mortality registry (source 1) and cancer registry (source 2) data from the health deputy in Fars province. In addition, we collected cancer cases from different hospitals (source3) between 2000 and 2005. We followed the cancer patients from the date of diagnosis up to the date of death.. We selected 10 most common cancer types in this study. If any of the patients died during 2003-2005 enter to this study. We compared mortality data from the three sources using capture recapture method using log linear modeling. Result: We collected 44863 data in which 9401was evaluated and finally 2232 enter to the study. Sensitivity of the mortality registry was 58% and based on the best model estimated number of cases was 3309 instead of the observed number. Conclusion: Coverage of the mortality registry for cancer death was weak leading to an underestimation in the mortality rate of the Fars Province. Improvement of the mortality registry is needed before making any firm decision about burden of cancer.

Abstract Background & objectives: Prematurity is the major cause of neonatal mortality, so this study aimed to determine the perinatal factors related to the premature infant’s mortality. Material & Method: Sample of records of this historical cohort study, was premature infants hospitalized in the Qhaem hospital intensive care unit, since 2007 to 2010. Two hundred cases were randomly selected. After the sample loss, 172 files precisely were studied from admission to discharge. Data were collected using a validated researcher made questionnaire, analyzed with SPSS19th, and presented with descriptive statistics, Fisher’s exact test, chi-square and T tests. Results: From 172 neonates based on death or alive until 28th day after birth, 54 and 118 were included in the case and control groups, respectively. Birth weight and gestational age of the subjects, were 1549.54(±635.42) g and 31.46 (±3.35) weeks, respectively. Antenatal taking of nitroglycerin, magnesium sulfate, methyldopa, hydralazine and chronic use of insulin were not significantly deferent in the two groups (P>0.05), and had Odds ratio more than 1. Diabetes, preeclampsia, maternal Rh and blood group, were significantly deferent between the two groups (P<0.05). In the birth room crying, breathing, cyanosis, tonicity, cord status, and a history of neonatal resuscitation (p<0.001) and neonatal clinical findings at the NICU admission time including apnea, bradycardia, gasping, hydrops, ascites, and IUGR (p<0.005) were significantly deferent between the two groups. Conclusion: Some of the maternal and neonatal perinatal factors could affect the premature neonates' mortality. Considering these factors could be effective in determining at risk neonates and providing factors in reducing mortality

Abstract Background & objectives: Acute myocardial infarction is the single most common cause of death in large parts of the world. Although the mortality rate after admission for myocardial infarction has declined significantly over the last two decades but it still remains high. Therefore, the aim of this study was to determine hospital mortality and its related factor in patients with acute myocardial infarction hospitalized in Dr. Heshmat hospital. Material & Methods: In this cross-sectional study, we assessed medical records of 227 patients with acute Myocardial Infarction that hospitalized in CCU. Demographic and clinical factors were collected from the medical records. Data analysis was performed using SPSSv.16 software at P>0.05. Results: In-hospital mortality rate of acute myocardial infarction patients was 8.4%. In univariate analysis, condition of patients with acute myocardial infarction after hospitalization was related with number of hospitalization days (P<0.002), left ventricular ejection fraction (P<0.002) and previous history of acute myocardial infarction (P<0.014). In regression analysis, only left ventricular ejection fraction was related with Hospital mortality rate (P<0.019, OR=0.885). Conclusion: Despite applying of preventive programs and therapeutic improvements, hospital mortality rate also is high (8.4%).In present study, hospital mortality was related with number of hospitalization days, left ventricular ejection fraction and previous history of acute myocardial infarction.

Background & objectives: Ozone is one of the most important gaseous pollutants in the air, which is necessary to be evaluated in the case of its harmful effects on human health. The present study was performed to assess the rate of mortality and hospitalization due to cardiovascular disease and Chronic Obstructive Pulmonary Disease (COPD) which are attributed to ozone in the air of Tehran during last decade (2005-2015).

Materials and Methods: This study was a descriptive–analytic. Firstly, hourly data of ozone pollutant were taken from Tehran environmental protection agency and air quality control. Data were validated according to the WHO guidelines. Required statistical parameters were calculated for health effect quantifying. Finally, processed data were converted to required inputs for the AirQ software and health effects quantifying were performed.

Results: Results showed that the number of total mortality due to Ozone exposure was 8222 cases in the past decade. The total number of cardiovascular mortality attributed to ozone in the past decade was 5951 people and the total number of respiratory mortality attributed to ozone in the past decade was 2947 people between 2005-2015.

Conclusions: According to the results, ozone has adverse effects on human health. Regarding the high levels of air pollution in Tehran and mortality and its related health consequences, appropriate measures should be taken to reduce the air pollution.