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Showing 5 results for Preterm
Efficacy of celecoxib, indomethacin and magnesium sulfate to stop preterm labor
N Moslemizadeh, K Yosofnejad , H Khani, M Rezaee M, S Samadi,
Volume 4, Issue 1 (6-2012)
Abstract

Abstract Background & Objectives: In human preterm birth refers to the birth of a baby with less than 37 weeks gestational age. Preterm labor is defined as the initiation of uterine contractions of sufficient frequency and intensity leading to progressive effacement and dilation of the cervix every time between 20 and 37 wk gestational age. The purpose of this study was to determine the celecoxib effectiveness on stopping preterm labor compared to indomethacin and magnesium sulfate. Materials & Methods: This study is a double-blind clinical trial on 400 patients between 24 to 34 weeks with a diagnosis of preterm labor in the Imam Khomeini hospital in Sari during 2009-10. This was a randomized study of patients who had twin pregnancy and intact amniotic membrane, do not responding to treatment with hydration and analgesics and cervical dilatation and effacement was on the rise. patients were divided into three groups receiving magnesium sulfate, indomethacin and celecoxib. In order to measure the Amniotic Fluid Index (AFI), Ultrasonography was carried out at 24, 48, and 72 hours after beginning of the treatment. Results: 400 patients mean age 26.1±4.6 years completed the trial. A significant statistical difference in favor of celecoxib was observed between these groups. Totally, 87.9% of patients used celecoxib and magnesium sulfate were respond to tocolysis. Conclusion: Celecoxib is as effective as magnesium sulfate for primary tocolysis.


Maternal risk factors contributing to preterm birth
M Zarei , Z Paydar, A Irandoost ,
Volume 7, Issue 4 (2-2016)
Abstract

Background and Objectives: The complications of preterm birth constitute the most common causes of death in infants. The purpose of this study was to identify maternal risk factors contributing to preterm birth.

Materials and Methods: This was an analytical research (case-control) which was carried out in 2010 in Shohada Hospital in Quchan. The questionnaires were completed via personal interviews and the collected data were analyzed (CI: 95%) with SPSS v.17 statistical software using descriptive analyze.

Result: The results indicated that the most frequent risk factors for preterm birth were multiparity (25%), PROM (8.3%), preeclampsia (8.3%) and renal diseases (6.7%).

Conclusions: According to the results of this study, devoting more attempts to promoting the quality and quantity of mothers' information about the risk factors of preterm infant birth and emphasizing the pre- pregnancy and during pregnancy cares can play a significant role in reducing the birth of preterm infants.

Keywords: Infant, Preterm, premature


Using Donabedian's model to evaluate quality of developmental care in neonatal intensive care units
Sh Torkzahrani , F Soleimani , H Rafiey, M Salavati , M Nasiri ,
Volume 8, Issue 2 (10-2016)
Abstract

Background & Objectives: Neuro-developmental cares refer to a wide range of interventions which are designed to reduce environmental stress and improve the living conditions of premature infants who are hospitalized in neonatal intensive care units. The aim of this study was to evaluate developmental care based on the three-part model of structure, process, and outcome.

Material & Methods: This cross-sectional study was conducted by 390 nurses and 200 pre-term infants from 27 of level III- NICU in Tehran. Data were collected with valid and reliable tools included structure's check list, developmental care's questionnaire, and outcome's check list. Data were analyzed using descriptive statistics and Pearson correlation coefficient with SPSS version 21.

Results: The average age of the infants was 32.90 weeks. The average of quality scores of structure and developmental care were 43.06% and 72.29%, respectively. Mean time of started oral feeding and length of hospital stay were 5.28 and 11.49 days, respectively with a weight difference of 408.80 gr. There was correlation between "sensory cares" and "daily cares" with length of hospital stay and started oral feeding. There was also correlation between "family cares" with weight difference and started oral feeding. There was also correlation between "sleep and pain care" and weight difference.

Conclusion: Structure and process of developmental care require more attention. The correlation between the areas of structure and process with outcome measures indicated that the Donabedian's model is effective to assess the quality of developmental cares.


The Relationship Between Maternal Serum Levels of Calcium, Phosphorus and Magnesium with Preterm Labor: A Case-Control Study
Hojatallah Ehtesham Manesh, Narges Sefidi, Toba Farazmand, Shahin Mafinezhad, Ghasem Bayani, Mina Noruzi Khalili, Ali Abbaszade, Mahsa Rahimian,
Volume 12, Issue 3 (12-2020)
Abstract
Introduction: Preterm delivery is one of the essential midwifery problems, which causes a large proportion of infant mortality even in advanced societies. Despite advances in pregnancy care, the frequency of preterm delivery has not decreased. This study aimed to determine the relationship between serum calcium, phosphorus, and magnesium level with preterm labor in pregnant women.
Methods: In this descriptive-analytic study, 40 mothers with full-term and 40 mothers with preterm labor were enrolled. Serum levels of calcium, phosphorus, and magnesium were compared and compared. Data were analyzed by SPSS 19 software using statistical tests. The significance level was considered 0.05.
Results: In the present study, mean (standard deviation) serum calcium, phosphorus, and magnesium levels respectively were 8.65 (0.72), 3.65 (0.57), and 1.89 (0.47). It was reported mmol / l and in mothers with term labor 8.8 (0.55), 3.53 (0.71) and 1.79 (0.17) mmol / lit, respectively. There was no significant difference between the two groups in the salts.
Conclusions: The results of our study showed no difference in serum levels of calcium, phosphorus, and magnesium in the two groups of women with the term and preterm labor. However, further studies with a higher sample size are needed.

Comparison of the Frequency of Vaginal Infections in Women with Premature Delivery and Women with Term Delivery in Ali Ibn Abitaleb Hospital of Zahedan in 2018
Hamid Reza Kouhpayeh, Mahdi Jahantigh, Azade Nazari, Mojgan Mokhtari,
Volume 15, Issue 3 (10-2023)
Abstract
Introduction: Premature birth is one of the most common causes of infant mortality worldwide. In many countries, preterm birth rates increased between 1990 and 2010. Vaginal infections are important causes of preterm labor (PTL). Therefore, this study aimed to determine the role of vaginal infections in causing preterm labor.
Method: This study was a case-control study. The target population was pregnant women referring to Ali Ibn Abitaleb Hospital in Zahedan, Iran, in 2018 who were aged 20 to 38 years and were diagnosed with PTL. The control group included an equal number of women with the same age range but term labor. To investigate candida, trichomonas, bacterial vaginosis, and group B streptococcali, swab samples were taken from the vagina and rectum. Different laboratory methods were performed to isolate the above-mentioned microorganisms, including microscopy of wet mount smear, Gram stain, culture on Sabouraud agar, and 5% sheep blood agar. Moreover, four Amsel criteria were used to diagnose bacterial vaginosis. At last, the collected data were analyzed by SPSS-19 software with a p-value of 0.05.
Results: A total of 300 patients were included in the study, and the mean age was not statistically significantly different between the two groups of PTL and term labor. No statistically significant difference was observed in the frequency of vaginal candidiasis (P=0.081), bacterial vaginosis (P=0.906), and trichomonas infection (P=0.904) between the two groups.
Conclusion: It seems that the genital infections examined in this study do not play a role in increasing the prevalence of premature birth.

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