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Showing 3 results for Schizophrenia

M Haresabadi, B Bibak , E Hosein Zadeh, M Bayati, M Arki, H Akbari,
Volume 4, Issue 2 (9-2012)
Abstract

Abstract Background & Objective: Schizophrenia is considered as one of the most extreme mental illnesses in the area of psychiatry which is characterized by social and occupational incompetence. Support and care of these patients has always been on the part of families. The imposed burden includes physical, mental, social and economic problems being experienced by caregiver of the family. The present study aimed at investigating the burden experienced by schizophrenic patients at Imam Reza Hospital in the city of Bojnurd. Material & Methods: This is a descriptive-analytical study conducted on 75 family caregivers visiting Imam Reza Hospital. Data collection methods included demographic questionnaire, and Zarit Questionnaire which measured degree of experienced burden by caregivers. Reliability and validity of both questionnaires had already been established. Then, data were fed into SPSS 14 for analysis. Results: 12.2% of caregivers experienced low burden, 36.4% average burden, and 51.5% high burden. The perceived burden among women was significantly higher (P=0.003) than that of men. There was significant relationship (p=0.03) between the obtained score of caregiving and age of caregivers while the relationship between caregiving score and age of patients was not significant (p>0.05) but was negative. Younger patients imposed higher burden on the caregivers. Conclusion: Taking care of schizophrenic patients put immense pressure on family especially on caregivers. Therefore, it can be said that the mental pressure imposed by such patients threatens caregivers' mental health, hence reduction in quality of care and support. Consequently, family centered programs are recommended for decreasing the burden incurred by schizophrenic patients


P Hashemian , M Edris Sedaghati ,
Volume 7, Issue 4 (2-2016)
Abstract

Background & Objectives: Relationship between family functioning and psychological characteristics of the individual is one of the most important discussions of family therapy. Schizophrenia and bipolar I disorder are very common in hospitalized patients. So we decided to investigate and campare the family functioning between these two groups of patients.

Material & Methods: In this case control study 50 patients with schizophrenia , 50 patients with bipolar I disorder and control group consists of 50 different professions were evaluated by family assessment device scale (FAD-I). Final results of the three groups were compared by SPSS V21 software.

Results: Findings indicate a significant difference between the two groups with the control group. Family dysfunction in patients with schizophrenia in both sexes was more severe than patients with bipolar I disorder. But in terms of age, significant differences between the two groups was found only in patients 20 to 40 years.

Conclusion: Based on the results of this study due to more severe impairment of family functioning  in patients with schizophrenia, it seems that family therapy as an adjunctive treatment could be helpful.

Key words: Family functioninig , Schizophrenia, Bipolar I disorder


Vahid Shahriari, Narges Azad,
Volume 15, Issue 3 (10-2023)
Abstract

Introduction: Schizophrenia is a chronic and debilitating mental disorder associated with psychosocial dysfunction and reduced quality of life. Neurosteroids modulate the functions of the brain and affect the activities of neurotransmitters. The present study aimed to investigate the relationship between the serum level of dehydroepiandrosterone sulfate (DHEAS) and executive function in patients with schizophrenia compared to the control group.
Method: In this case-control study, 20 schizophrenic men hospitalized in the psychiatric department of 5th Azar Hospital in Gorgan in 1401 and 20 non-diseased men eligible to enter the study were selected. After measuring the serum level of DHEAS, executive function was evaluated using the Wisconsin Card Sorting Test. Data analysis was performed in SPSS software (version 18) using independent t-test, U-Man-Whitney, logistic regression, chi-score, and Fisher's exact test at a significance level of 0.05.
Results: The two groups were similar in terms of age (P=0.4), marital status (P=0.06), and education level (P=0.1). There was no statistically significant difference in the serum level of DHEAS in the two groups. There was a statistically significant difference in the executive performance of the two groups in the items of spotting (P=0.001) and correct answers (P=0.002).
Conclusion: In this study, the level of DHEAS in subjects with schizophrenia was lower than that of healthy people. The serum level of this hormone was inversely associated with the duration of schizophrenia and had a direct linear relationship with executive function in the number of categories and perseverative errors. These results can guide relevant experts in the direction of timely diagnosis and treatment measures for these people.


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