Search published articles


Showing 4 results for Wound Healing

F Jahdie , F Eghdampour , A Haselie , M Kheyrkhah , H Hagani , Z Abasi ,
Volume 4, Issue 5 (3-2013)
Abstract

Abstract Background and Objective: Episiotomy is common perineal trauma in primiparous vaginal birth. Complications after episiotomy include inflammation, edema, dehiscence and perineal pain. Calendula has wound healing effects but there is little information about its application on episiotomy. Thus we aimed to study the effect of Calendula ointment on wound healing of episiotomy. the purpose of this study was to elevate the effectiveness of Calendula ointment on wound healing of episiotomy among primiparous women admitted in Lolagar hospital of Tehran, 2010. Material & Methods: the study was carried out using a randomized control trial method the population included primiparous who had the inclusion criteria of the study. The setting of the study Conducted on 74 primiparous women referred to Lolagar hospital in Tehran which were selected with random allocation method. The case group consisted of 37 women that consumed Calendula ointment and control group consisted of 37 women that consumed hospital’s routine care (Povidon Iodine). The data collection instruments were questionnaire and REEDA Scale (redness, Edema, Ecchmosis, Discharge and Approximation). Questionnaire was demographic, postpartum and neonatal items of primiparous mothers. Perineal wound healing was evaluated using REEDA Scale within 4 hours and 5 days after intervention. Data were analyzed by spss 16 softe ware and presented with chi-square and t-test . Result: Our findings showed that The REEDA score was significantly lower in the experimental group (Calendula ointment) 5 days after episiotomy (p=0.001). Conclusion: Considering the result of this study, it seems that Calendula ointment can be used in episiotomy wound care instead of Povidon Iodine solution because this compound has anti- inflammatory and antimicrobial properties that were more effective than Povidon Iodine in wound pain relief. This method suggested as a safe and effective method with minimal side effects.


, ,
Volume 5, Issue 1 (6-2013)
Abstract

Abstract Backgroud & Objective: Debridment necrotic tissues then healing under tissue is one of the necessary intervention in management burn wounds. The presence of necrotic tissue is an important problem in patients with deep burns. This study compare topical effectivness of kiwifruit versus Elase pomade on removal of necrotic tissue of full-thickness burns in male rats. Material & Methods: In this experimental study, were selected 10 vistar rats. After anesthesia by ketamin and xylosine, both flanks of rats were shaved. Then full thickness burns with 3cm diameter were produced using boiling water. Rats were divided into 3 groups randomly. One side of the first was treated by elase pomade and the other side of the first was treated by elase pomade and the othere side in group was used from topical kiwifruit. Results:Findings showed that kiwifruit debridement time with 5/7days was related to elase pomade(p=0/001). also this difference was significant in elase groups(p=0/001). On the other hand there was relatively no significant difference between debridement time in two control groups. In addition neo-epithelialization and healing were faster other groups. Conclusion: The result of research indicate that using topical kiwifruit not only causes no injury to healthy tissues but also can be debridement in the short time. Findings this study can open new horizons and provid a new treatment modality for burns.


K Shahanipour, M Sadeghi ,
Volume 8, Issue 1 (6-2016)
Abstract

Background & objective: Honey and Aloe vera have traditionally used for its healing effects on burn wounds. The aim of this study was to investigate the effect of honey and aloe vera on the burn wound healing process in rat.

Materials & Methods: This was an experimental study performed on 24 adult male rats. Following ether anesthesia, a second degree burn wound of 250mm2 was made on back of each rat. After confirming burns, the rats were divided into 4 groups (6 in each group).Control group, group 1 treated with Honey and Aloe vera, group 2 treated with Aloe vera and group 3  treated with Honey three times per day. Evaluation was made through measuring the area of the healed region and data were analyzed using one way ANOVA test.

Results: This study was indicated of a decrease of 123 ±34/024 mm2 in burn wounds size after treatment  in honey and Aloe vera group which was greater than those in others(P-value =0/009)  and  honey group was only shown to have   decreased the burn wounds size greater than the Aloe vera group.

Conclusion: Combination of honey and aloe vera was found to have more healing potential on second-degree burn wound. Faster healing process, less complications and easy availability of honey and Aloe vera are among the reasons suggesting more clinical trials using this preparation.

Key words: Burn, Honey, Aloe vera, wound healing.


Seyedeh Mahsa Mousavi, Maryam Nikzad, Seyed Ali Asghar Ghoreyshi, Maedeh Sadat Mohammadi,
Volume 10, Issue 1 (3-2018)
Abstract

Introduction: Nanocellulose is an exclusive natural substance extracted from lignocellulosic biomass, which attracted the attention of many researchers regarding its medical application during the recent years, owing to their remarkable physical, chemical, and biological properties such as biocompatibility, biodegradability, and low toxicity. The current study aimed at reviewing cellulose types and their application in medicine including drug delivery, tissue engineering, implants and substitute materials in body, and antibacterial agents.
Methods: This review study was conducted searching keywords in online databases such as Wiley Online Library, Google Scholar, ScienceDirect, Springer, and PubMed in English language. A total of 300 full-text articles and abstracts were extracted, which some of them were excluded due to irrelevant contents. Finally, the eligible articles were selected and investigated.
Results: Generally, three types of nanocellulose as nanofiber, nanocrystal, and bacterial celluloses were introduced, which their application in medical products improved mechanical and biological properties, reduced toxicity, etc. Although during the last decade several successful nanocellulose-based products were introduced, a significant improvement in cellulose biomedical materials is expected. Totally, innovation of reliable manufacturing methods for biocompatible cellulose materials with controlled certain properties, functionalization of the surface, and dispersion for pharmaceutical and biomedical applications are required.
Conclusions: Among the different types of nanocellulose, bacterial nanocellulose are widely utilized in recent years for biomedical applications, owing to their low toxicity and high porosity.


Page 1 from 1     

© 2025 CC BY-NC 4.0 | Journal of North Khorasan University of Medical Sciences

Designed & Developed by: Yektaweb