Volume 16, Issue 4 (winter 2025)
2025, 16(4): 87-96 |
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Ethics code: IR.UMA.REC.1401.033
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Alikhani A, Ghiyami S H, Bahram M E. Effect of Eight Weeks of Combined Exercises and Consumption of Mulberry Leaf Extract on the Levels of Liver Enzymes in Elderly Males with Type 2 Diabetes. North Khorasan University of Medical Sciences 2025; 16 (4) :87-96
URL: http://journal.nkums.ac.ir/article-1-3117-en.html
URL: http://journal.nkums.ac.ir/article-1-3117-en.html
1- Graduate Student of Sports Physiology, Department of Physical Education and Sports Sciences, Raja University, Qazvin, Iran
2- Ph.D. in Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran ,hamedghiyami88@gmail.com
3- Ph.D. in Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
2- Ph.D. in Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran ,
3- Ph.D. in Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
Abstract: (300 Views)
Introduction: Type 2 diabetes causes structural and functional changes in the liver to increase the serum levels of liver enzymes. In this regard, the present study aimed to investigate the effect of eight weeks of combined exercises and the consumption of black mulberry leaf extract on the levels of liver enzymes in elderly males with type 2 diabetes.
Method: In this semi-experimental study, 40 elderly males with type 2 diabetes were selected and randomly divided into five groups of 8 cases, namely control, placebo, black mulberry leaf extract, exercise, and black mulberry leaf extract+exercise. The exercises were performed for eight weeks, with three 90-minute sessions per week. Furthermore, 3,000 mg of mulberry leaf extract per day was prescribed along with three main meals. The data were analyzed in SPSS software (version 27) using the two-way ANOVA test at a significance level of 0.05.
Results: Interactive effect of exercise and extract on the values of AST (P=0.001, effect size 0.420), ALP (P=0.001, effect size 0.525), ALT (P=0.001, effect size 0.511), and glucose (P=0.001, effect size 0.460) was significant. Furthermore, a significant decrease was observed in ALT, AST, ALP, and blood glucose levels of the exercise, extract, and exercise+extract groups (P<0.05). The extract+exercise group underwent a greater decrease in the values of AST (20%), ALP (12.90%), ALT (22.30%), and glucose (12%), compared to the pre-test stage.
Conclusion: Implementation of eight weeks of combined exercises and consumption of black mulberry leaf extract seems to improve liver enzymes in elderly males with type 2 diabetes.
Method: In this semi-experimental study, 40 elderly males with type 2 diabetes were selected and randomly divided into five groups of 8 cases, namely control, placebo, black mulberry leaf extract, exercise, and black mulberry leaf extract+exercise. The exercises were performed for eight weeks, with three 90-minute sessions per week. Furthermore, 3,000 mg of mulberry leaf extract per day was prescribed along with three main meals. The data were analyzed in SPSS software (version 27) using the two-way ANOVA test at a significance level of 0.05.
Results: Interactive effect of exercise and extract on the values of AST (P=0.001, effect size 0.420), ALP (P=0.001, effect size 0.525), ALT (P=0.001, effect size 0.511), and glucose (P=0.001, effect size 0.460) was significant. Furthermore, a significant decrease was observed in ALT, AST, ALP, and blood glucose levels of the exercise, extract, and exercise+extract groups (P<0.05). The extract+exercise group underwent a greater decrease in the values of AST (20%), ALP (12.90%), ALT (22.30%), and glucose (12%), compared to the pre-test stage.
Conclusion: Implementation of eight weeks of combined exercises and consumption of black mulberry leaf extract seems to improve liver enzymes in elderly males with type 2 diabetes.
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2024/01/15 | Accepted: 2024/04/15 | Published: 2025/01/1
Received: 2024/01/15 | Accepted: 2024/04/15 | Published: 2025/01/1
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