Volume 14, Issue 4 (3-2023)
2023, 14(4): 47-54 |
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Ethics code: IR.GOUMS.REC.1400.023
Clinical trials code: IRCT20221020056250N1
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Alinaghimaddah S M, Akbari M R, Tabrizi K K, Ownagh V, Hatami S E. Comparison of the Effects of Midazolam, Propofol, and Dexmede-tomidine on Hemodynamics Variation in Patients Undergoing Cataract Surgery under Local Anesthesia at 5th Azar Hospital in Gorgan in 2021-2022. North Khorasan University of Medical Sciences 2023; 14 (4) :47-54
URL: http://journal.nkums.ac.ir/article-1-2696-en.html
URL: http://journal.nkums.ac.ir/article-1-2696-en.html
Seyede Mahrokh Alinaghimaddah * 
1, Mohammad Reza Akbari2 , Kazem Kazemnejad Tabrizi3 , Vahid Ownagh4 , Seyed Esmaeil Hatami5
1, Mohammad Reza Akbari2 , Kazem Kazemnejad Tabrizi3 , Vahid Ownagh4 , Seyed Esmaeil Hatami5
1- Assistant Professor of Anesthesiology, Department of Anesthesiology and Critical Care, School of Medicine, 5th Azar Hospital, Sayyad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran , alinaghi@yahoo.com
2- Anesthesiologist, Department of Anesthesiology and Critical Care, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
3- Associate Professor of Anesthesiology, Department of Anesthesiology and Critical Care, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
4- Ophthalmologist, Ophthalmology Division, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
5- M.Sc. of Epidemiology, Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
2- Anesthesiologist, Department of Anesthesiology and Critical Care, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
3- Associate Professor of Anesthesiology, Department of Anesthesiology and Critical Care, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
4- Ophthalmologist, Ophthalmology Division, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
5- M.Sc. of Epidemiology, Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
Abstract: (1152 Views)
Introduction: Cataract surgery is a common surgery, especially among the elderly, and the choice of anesthesia medications is critical in such patients. In this study, the effects of midazolam, propofol, and dexmedetomidine were investigated for sedation in patients undergoing cataract surgery under local anesthesia.
Method: Ninety patients were included in this study and underwent cataract surgery using class II and III anesthesia (according to the ASA criteria). They were also randomly assigned to three groups. The first group received midazolam, the second group received propofol, and the third group received dexmedetomidine. During the surgery and recovery phase, blood pressure, arterial blood oxygen saturation, heart rate, and the occurrence of complications were recorded. Data were analyzed using the SPSS software (version 23) at a significance level of 0.05.
Results: Alterations in arterial blood oxygen saturation (SpO2) levels were not significantly different among the three groups (P>0.05); however, there were fewer changes in SpO2 levels at recovery in the propofol group (P<0.05). Moreover, alterations in blood pressure did not differ significantly across the three groups during the surgery (P>0.05), whereas during the recovery, they were lower in the group receiving dexmedetomidine (P>0.05). Finally, Heart rates were not significantly different among the three groups during surgery and recovery (P>0.05).
Conclusion: The results demonstrated that in patients with hypertension and tachycardia, dexmedetomidine may be a better choice for sedation.
Method: Ninety patients were included in this study and underwent cataract surgery using class II and III anesthesia (according to the ASA criteria). They were also randomly assigned to three groups. The first group received midazolam, the second group received propofol, and the third group received dexmedetomidine. During the surgery and recovery phase, blood pressure, arterial blood oxygen saturation, heart rate, and the occurrence of complications were recorded. Data were analyzed using the SPSS software (version 23) at a significance level of 0.05.
Results: Alterations in arterial blood oxygen saturation (SpO2) levels were not significantly different among the three groups (P>0.05); however, there were fewer changes in SpO2 levels at recovery in the propofol group (P<0.05). Moreover, alterations in blood pressure did not differ significantly across the three groups during the surgery (P>0.05), whereas during the recovery, they were lower in the group receiving dexmedetomidine (P>0.05). Finally, Heart rates were not significantly different among the three groups during surgery and recovery (P>0.05).
Conclusion: The results demonstrated that in patients with hypertension and tachycardia, dexmedetomidine may be a better choice for sedation.
Type of Study: Orginal Research |
Subject:
Clinical
Received: 2022/04/30 | Accepted: 2022/11/8 | Published: 2023/02/26
Received: 2022/04/30 | Accepted: 2022/11/8 | Published: 2023/02/26
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