Abstract Background & Objectives: Assessment and predictor systems of outcome have been presented in order to estimate the risk of anesthesia in cardiac surgery. Regarding to the importance of outcome prediction we aimed to determine how CARE-Score could predict the outcome (morbidity and mortality) of patients in cardiac surgery Material &Methods: This is a descriptive-cohort study that accomplished on 130 cardiac patients in cardiac surgery department in Imam Reza Hospital, Mashhad. The sampling was done in a period 3 months. In order to collection the information, we used the sample selection sheet, demographic sheet, informative sheet, CARE-SCORE and morbidity form. This study aimed to determine the relationship between tested quantitative variables using the Pearson correlation coefficient . 95% confidence (α = 0/05) were considered. Data analysis was performed using spss software version 12. Results: The results showed a significant relationship between CARE-SCORE and morbidity (r = 0.86, p<0.001), CARE-SCORE and hospital stay (r =0.72, p<0.001). The patients with the higher score had more morbidity and lengthen hospital stay. Conclusion: As regards, CARE-SCORE can predict the morbidity after the cardiac surgery simply, we advise the Anesthesiologist to use this predictive model in cardiac surgery units preoperatively
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