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JNKUMS 2011, 3(2): 29-33 Back to browse issues page
Unnecessary antibiotic therapy in children with diarrhea may cause antibiotic resistance
A Khakhshour , M Taherpour , F Khorashadi Zadeh , I Maddi , S Nojomi , Zh Shaikhi
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Abstract Background & Objectives: Growing Antibiotic resistance is rapidly increasing in both developed and developing countries. Diarrheal disease is a leading cause of morbidity and mortality in children that treats with antibiotics. This study was conducted to evaluate correct prescription of antibiotics in children less than 5 years old in hospitalized for diarrhea with at Imam Reza hospital in Bojnord 1389. Methods & Materials: A total of 292 children, aged less than 5 years old with diarrhea were recruited in this one group cross-sectional study. Sampling design was non-random, purposeful sampling. The clinical history, socio-demographic characteristics, physical examination findings and laboratory finding were recorded in tree questionnaires. All data were analyzed by t-test, one-way ANOVAs, chi-square and correlation using SPSS 11. Results: 53% children were male. 73% patients had vomiting and fever.42% had abdominal pain and 24% had dehydration. Antibiotics were prescript for 79% of patients70 % prescribed on antibiotics was incorrect. There was a significant relation between negative stool exam and misuse of antibiotics (P <.05). Kapa agreement coefficient was 0.125 that means invert relation. Conclusion: prescription of antibiotics must be according stool culture and diagnostic tests. Most attention should be payed to common viral diarrhea in hospitalized children to prevent antibiotics resistance.

Keywords: Keywords: Antibiotic resistance, Children, Diarrhea
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Type of Study: Orginal Research | Subject: Basic Sciences
Received: 2015/01/5 | Accepted: 2015/01/5 | Published: 2015/01/5
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Khakhshour A, Taherpour M, Khorashadi Zadeh F, Maddi I, Nojomi S, Shaikhi Z. Unnecessary antibiotic therapy in children with diarrhea may cause antibiotic resistance. JNKUMS. 2011; 3 (2) :29-33
URL: http://journal.nkums.ac.ir/article-1-206-en.html

Volume 3, Issue 2 (summer 2011 2011) Back to browse issues page
مجله دانشگاه علوم پزشکی خراسان شمالی Journal of North Khorasan University of Medical Sciences
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