Journal of North Khorasan

Abstract Background & objective: Postoperative sore throat is a common complication of anesthesia that is prevalent in patients after laryngeal tubing. Glucocorticoids are inflammatory response and hydrocortisone may have potential advantages in the prevention of postoperative sore throat. The aim of this study was evaluate the efficacy of intravenously administered hydrocortisone in reducing the incidence and severity of postoperative sore throat in patients receiving general anesthesia with laryngeal mask airway insertion. Materials &Methods: Sixty patients aged 20-60 years who were candidate for urogenital surgeries under general anesthesia, were randomly divided into 2 groups. Group 1 were received hydrocortisone 100 mg (2mL) and group 2 (placebo) were received normal saline 2mL intravenously 5 minutes before induction of anesthesia. At the end of the surgical operation, the patients were asked about sore throat symptoms at the recovery, the second, and the fourth and at twenty four hours after the end of the surgery. Sore throat was graded using a 4-point scale and was evaluated by an anesthesiologist who was unaware to the type of the treatment. Results: Postoperative sore throat was seen in three cases (10%) in the hydrocortisone group and in six cases (20%) in the placebo group. there was no statistically significant differences between two groups. Neither moderate nor sever pains were observed in any of the postoperative periods in patients of both groups. There were no statistically significant differences in regards of pain in all intervals after recovery between two groups. Conclusion: According to our findings, intravenous administration of hydrocortisone 5 minutes prior to the induction of anesthesia had no effects on the severity of postoperative sore throat in urogenital surgeries.