Volume 15, Issue 1 (Spring 2023)
2023, 15(1): 34-42 |
Back to browse issues page
Ethics code: IR.IAU. SARI.REC.1400.004
Clinical trials code: IRCT20190831044650N3
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Akbari R, Jafari Chashmy A, Habibian M. The Effect of Sports Activity and Vitamin D Intake on Serum Eutoxin-1 and Superoxide Dismutase Levels in Overweight Women with Vitamin D Deficiency: A Clinical Trial Study. North Khorasan University of Medical Sciences 2023; 15 (1) :34-42
URL: http://journal.nkums.ac.ir/article-1-2745-en.html
URL: http://journal.nkums.ac.ir/article-1-2745-en.html
1- Ph.D. Student in Sports Physiology, Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran
2- Assistant Professor, Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran ,jafarychashmy@gmail.com
3- Associate Professor, Department of Physical Education and Sports Sciences, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran
2- Assistant Professor, Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran ,
3- Associate Professor, Department of Physical Education and Sports Sciences, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran
Abstract: (1101 Views)
Introduction: Being overweight and having vitamin D deficiency are associated with oxidative stress and low-grade chronic inflammation, resulting in various diseases. In the present study, changes in the levels of Eutoxin-1 and superoxide dismutase (SOD) were evaluated after 8 weeks of high-intensity interval resistance training (HIIRT) and vitamin D intake in overweight women with vitamin D deficiency.
Method: In this clinical trial study, 52 overweight women with vitamin D deficiency were purposefully selected and then randomly assigned to exercise, vitamin D, exercise+vitamin D (combined), and control groups. HIIRT was performed 3 times a week in three sets with an intensity of 80% of a maximum repetition. Vitamin D was taken at a dose of 50,000 units weekly. Data were analyzed using paired t-test, one-way ANOVA, and Kruskal-Wallis tests with a significant level of less than 0.05.
Results: After 8 weeks, SOD activity increased in the experimental groups, and the level of Eutoxin-1 decreased significantly. In addition, the rate of changes in SOD and Eutoxin-1 levels in the combined group was higher than those in the vitamin D group; however, no significant difference was observed between the exercise and combination groups (P<0.05).
Conclusion: It seems that HIIRT and vitamin D intake can increase SOD activity and up-regulate Eutoxin-1 in overweight women. Moreover, co-administration of HIIRT with vitamin D intake can have stronger effects in reducing the inflammatory-oxidative effects of overweight and vitamin D deficiency by increasing SOD and decreasing Eutoxin-1, compared to the intervention of vitamin D consumption.
Method: In this clinical trial study, 52 overweight women with vitamin D deficiency were purposefully selected and then randomly assigned to exercise, vitamin D, exercise+vitamin D (combined), and control groups. HIIRT was performed 3 times a week in three sets with an intensity of 80% of a maximum repetition. Vitamin D was taken at a dose of 50,000 units weekly. Data were analyzed using paired t-test, one-way ANOVA, and Kruskal-Wallis tests with a significant level of less than 0.05.
Results: After 8 weeks, SOD activity increased in the experimental groups, and the level of Eutoxin-1 decreased significantly. In addition, the rate of changes in SOD and Eutoxin-1 levels in the combined group was higher than those in the vitamin D group; however, no significant difference was observed between the exercise and combination groups (P<0.05).
Conclusion: It seems that HIIRT and vitamin D intake can increase SOD activity and up-regulate Eutoxin-1 in overweight women. Moreover, co-administration of HIIRT with vitamin D intake can have stronger effects in reducing the inflammatory-oxidative effects of overweight and vitamin D deficiency by increasing SOD and decreasing Eutoxin-1, compared to the intervention of vitamin D consumption.
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2022/05/9 | Accepted: 2023/01/31 | Published: 2023/05/27
Received: 2022/05/9 | Accepted: 2023/01/31 | Published: 2023/05/27
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
