Volume 16, Issue 4 (winter 2025)
2025, 16(4): 77-86 |
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Ethics code: IR.HSU.REC.1402.016
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Ebrahimi M, Hejazi K, Haghighi A, Rahimi N. Eeffect of Eight Weeks of Moderate Intensity Interval Training with Selenium Supplementation on Oxidative Stress Levels, Body Composition, and Functional Indices in Women with Hypothyroidism. North Khorasan University of Medical Sciences 2025; 16 (4) :77-86
URL: http://journal.nkums.ac.ir/article-1-3116-en.html
URL: http://journal.nkums.ac.ir/article-1-3116-en.html
1- MSc in Sport Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
2- Assistant Professor in Sport Physiology, Department of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran ,k.hejazi@hsu.ac.ir
3- Professor in Sport Physiology, Department of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
4- Assistant professor, Department of Internal Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
2- Assistant Professor in Sport Physiology, Department of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran ,
3- Professor in Sport Physiology, Department of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran
4- Assistant professor, Department of Internal Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
Abstract: (376 Views)
Introduction: Thyroid diseases are common health issues worldwide, especially among women. The occurrence of thyroid diseases is increasingly associated with oxidative stress. The present study aimed to assess the effect of eight weeks of moderate intensity interval training with selenium supplementation on oxidative stress levels, body composition, and functional indices in women with hypothyroidism.
Method: In this quasi-experimental study, 46 women with hypothyroidism were randomly assigned to four groups: placebo, selenium supplement, moderate-intensity interval training+ selenium, and moderate-intensity interval training+placebo. Selenium tablets contain 200 micrograms of selenium and placebo contains chickpea flour, which should be taken daily in one meal before exercise. The exercise program consisted of eight weeks, three sessions per week, each lasting 20-40 minutes at an intensity equivalent to 60%-80% of maximum heart rate. Paired t-test was used for intragroup changes, and one-way analysis of variance with repeated measures was employed for between-group changes.
Results: The results indicated significant statistical differences in the time interaction changes within the groups in variables, such as body weight (P=0.001), body mass index (P=0.001), body fat percentage (P=0.001), malondialdehyde (P=0.001), glutathione peroxidase (P=0.004), muscle endurance (P=0.001), and hand grip strength (P=0.001).
Conclusion: As evidenced by the findings of the current study, it is likely that intermittent moderate-intensity exercise with selenium supplementation can be used to improve thyroid hormones and prevent the negative effects of hypothyroidism in women.
Method: In this quasi-experimental study, 46 women with hypothyroidism were randomly assigned to four groups: placebo, selenium supplement, moderate-intensity interval training+ selenium, and moderate-intensity interval training+placebo. Selenium tablets contain 200 micrograms of selenium and placebo contains chickpea flour, which should be taken daily in one meal before exercise. The exercise program consisted of eight weeks, three sessions per week, each lasting 20-40 minutes at an intensity equivalent to 60%-80% of maximum heart rate. Paired t-test was used for intragroup changes, and one-way analysis of variance with repeated measures was employed for between-group changes.
Results: The results indicated significant statistical differences in the time interaction changes within the groups in variables, such as body weight (P=0.001), body mass index (P=0.001), body fat percentage (P=0.001), malondialdehyde (P=0.001), glutathione peroxidase (P=0.004), muscle endurance (P=0.001), and hand grip strength (P=0.001).
Conclusion: As evidenced by the findings of the current study, it is likely that intermittent moderate-intensity exercise with selenium supplementation can be used to improve thyroid hormones and prevent the negative effects of hypothyroidism in women.
Keywords: Body composition, Hypothyroidism, Selenium, Moderate intensity interval training, Oxidative stress
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2023/11/1 | Accepted: 2024/05/1 | Published: 2025/01/1
Received: 2023/11/1 | Accepted: 2024/05/1 | Published: 2025/01/1
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