Volume 17, Issue 3 (Autumn 2025)
2025, 17(3): 1-10 |
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Kazeminasab F, Zafarmand O. Combined Effect of Exercise Training and Garlic Supplementation on Lipid Profiles in Adults: A Systematic Review and Meta-analysis. North Khorasan University of Medical Sciences 2025; 17 (3) :1-10
URL: http://journal.nkums.ac.ir/article-1-3260-en.html
URL: http://journal.nkums.ac.ir/article-1-3260-en.html
1- Assistant Professor, Department of Physical Education and Sport Science, School of Humanities, University of Kashan, Kashan, Iran
2- MSc in Exercise Physiology, Department of Physical Education and Sports Science, School of Humanities, University of Yasouj, Yasouj, Iran ,omidzafarmand2202@gmail.com
2- MSc in Exercise Physiology, Department of Physical Education and Sports Science, School of Humanities, University of Yasouj, Yasouj, Iran ,
Abstract: (313 Views)
Introduction: Physical activity and herbal supplements play a significant role in preventing and controlling obesity while creating optimal adaptation. The present study aimed to assess the combined effect of exercise training and garlic supplementation on lipid profiles in adults.
Method: A systematic search was conducted on PubMed, Web of Science, Scopus, SID, and Magiran databases for English and Persian published articles until August 2024. The mean difference and 95% confidence interval (CI) were calculated using a random-effects model. Heterogeneity was assessed by using the (I2) test, and publication bias was evaluated by visual funnel plot analysis and Egger's test. The data were analyzed in CMA2 software.
Results: A total of 5 studies and 117 subjects were included in the present meta-analysis. The results demonstrated that the combination of exercise training and garlic supplementation did not significantly change TC [WMD=-3.872 mg/dl (13.550 to -21.294), P=0.663], TG [WMD=-24.713 mg/dl (21.579 to -71.004), P=0.295], LDL [WMD=-1.477 mg/dl (34.720 to -37.675), P=0.936] and HDL [WMD=5.921 mg/dl(16.604 to -4.761), P=0.277] compared to the garlic supplementation group in adults.
Conclusion: The results of the present meta-analysis study indicated that the combination of exercise training and garlic supplementation did not cause significant changes in TC, TG, LDL, and HDL. The combination of exercise and garlic does not have a better effect on improving lipid profiles than garlic alone
Method: A systematic search was conducted on PubMed, Web of Science, Scopus, SID, and Magiran databases for English and Persian published articles until August 2024. The mean difference and 95% confidence interval (CI) were calculated using a random-effects model. Heterogeneity was assessed by using the (I2) test, and publication bias was evaluated by visual funnel plot analysis and Egger's test. The data were analyzed in CMA2 software.
Results: A total of 5 studies and 117 subjects were included in the present meta-analysis. The results demonstrated that the combination of exercise training and garlic supplementation did not significantly change TC [WMD=-3.872 mg/dl (13.550 to -21.294), P=0.663], TG [WMD=-24.713 mg/dl (21.579 to -71.004), P=0.295], LDL [WMD=-1.477 mg/dl (34.720 to -37.675), P=0.936] and HDL [WMD=5.921 mg/dl(16.604 to -4.761), P=0.277] compared to the garlic supplementation group in adults.
Conclusion: The results of the present meta-analysis study indicated that the combination of exercise training and garlic supplementation did not cause significant changes in TC, TG, LDL, and HDL. The combination of exercise and garlic does not have a better effect on improving lipid profiles than garlic alone
Type of Study: Review Article |
Subject:
Basic Sciences
Received: 2024/10/24 | Accepted: 2024/11/27 | Published: 2025/09/29
Received: 2024/10/24 | Accepted: 2024/11/27 | Published: 2025/09/29
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