Volume 16, Issue 1 (Spring 2024)
2024, 16(1): 12-20 |
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Ethics code: IR.KHU.KRC.1000.160
Clinical trials code: IRCT20220128053844N2
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Nakhzari Khodakheir J, Zarei M, Zolfi H R, Shakib A. The Effect of High-intensity Functional Training on LRG1 Levels and Its Relationship with Cardiovascular Risk Factors and Atherogenic Indices in Overweight and Obese Women. North Khorasan University of Medical Sciences 2024; 16 (1) :12-20
URL: http://journal.nkums.ac.ir/article-1-2920-en.html
URL: http://journal.nkums.ac.ir/article-1-2920-en.html
1- Assistant Professor, Department of Physical Education and Sport Sciences, School of Human Sciences, University of Zabol, Zabol, Iran , javadnakhzari@uoz.ac.ir
2- Assistant Professor, Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, University of Neyshabur, Neyshabur, Iran
3- Assistant Professor, Department of Physical Education and Sport Science, Technical and Vocational University (TVU), Tehran, Iran
4- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
2- Assistant Professor, Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, University of Neyshabur, Neyshabur, Iran
3- Assistant Professor, Department of Physical Education and Sport Science, Technical and Vocational University (TVU), Tehran, Iran
4- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
Abstract: (954 Views)
Introduction: The present study aimed to investigate the effect of high-intensity functional training on leucine-rich alpha-2 glycoprotein 1(LRG1) levels and its relationship with cardiovascular risk factors and atherogenic indicators in overweight and obese women.
Method: In this semi-experimental study, 19 overweight and obese women were randomly divided into two groups of high-intensity functional training (n=9) and control (n=10). The participants of the training group performed high-intensity functional exercises three times per week for eight weeks. Before and after the intervention, blood samples were taken to measure LRG1 concentration and lipid profile, in addition to the calculation of atherogenic indices. Analysis of covariance test was used to analyze the data.
Results: After eight weeks of high-intensity functional training, LRG1 concentration (P=0.027), plasma atherogenic index (P=0.000), Castelli risk index-I (CRI-I) (P=0.001), and Castelli risk index-II (CRI-II) (P=0.002) were significantly decreased in the experimental group compared to the control group. A positive and significant correlation was observed between changes in LRG1 concentration and changes in body fat percentage (r=0.437, P=0.041), plasma atherogenic index (r=0.512, P=0.025), and CRI-I (r=0.479, P=0.038). A negative and significant correlation was observed between the changes of LRG1 and high-density lipoprotein cholesterol (HDL-C) (r =-0.569, P=0.011).
Conclusion: Eight weeks of high-intensity functional training in overweight and obese women is effective in reducing LRG1 and improving cardiovascular risk factors and atherogenic indicators. Therefore, high-intensity functional exercises can be effective as auxiliary exercise interventions in controlling and reducing complications related to overweight and obesity
Method: In this semi-experimental study, 19 overweight and obese women were randomly divided into two groups of high-intensity functional training (n=9) and control (n=10). The participants of the training group performed high-intensity functional exercises three times per week for eight weeks. Before and after the intervention, blood samples were taken to measure LRG1 concentration and lipid profile, in addition to the calculation of atherogenic indices. Analysis of covariance test was used to analyze the data.
Results: After eight weeks of high-intensity functional training, LRG1 concentration (P=0.027), plasma atherogenic index (P=0.000), Castelli risk index-I (CRI-I) (P=0.001), and Castelli risk index-II (CRI-II) (P=0.002) were significantly decreased in the experimental group compared to the control group. A positive and significant correlation was observed between changes in LRG1 concentration and changes in body fat percentage (r=0.437, P=0.041), plasma atherogenic index (r=0.512, P=0.025), and CRI-I (r=0.479, P=0.038). A negative and significant correlation was observed between the changes of LRG1 and high-density lipoprotein cholesterol (HDL-C) (r =-0.569, P=0.011).
Conclusion: Eight weeks of high-intensity functional training in overweight and obese women is effective in reducing LRG1 and improving cardiovascular risk factors and atherogenic indicators. Therefore, high-intensity functional exercises can be effective as auxiliary exercise interventions in controlling and reducing complications related to overweight and obesity
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2023/10/25 | Accepted: 2023/11/20 | Published: 2024/03/26
Received: 2023/10/25 | Accepted: 2023/11/20 | Published: 2024/03/26
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