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2025, 17(1): 14-24 |
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Mohammadi M, Zareipour M A, Savabi-Esfahani M, Moshirinia F, Dehghan M, Khani A. Investigating the Protective Effects of Royal Jelly on Sperm Parameters in Animal Studies: A Narrative Review. North Khorasan University of Medical Sciences 2025; 17 (1) :14-24
URL: http://journal.nkums.ac.ir/article-1-3136-en.html
URL: http://journal.nkums.ac.ir/article-1-3136-en.html
Maryam Mohammadi1 
, Morad Ali Zareipour2 , Mitra Savabi-Esfahani3 , Fateme Moshirinia *4 , Maryam Dehghan5 , Alireza Khani6
, Morad Ali Zareipour2 , Mitra Savabi-Esfahani3 , Fateme Moshirinia *4 , Maryam Dehghan5 , Alireza Khani6
1- Nursing and Midwifery Care Research Center, Non-Communicable Diseases Research Institute, Shahid Sadougi University of Medical Sciences, Yazd, Iran
2- Assistant Professor, Department of Public Health, Khoy University of Medical Sciences, Khoy, Iran
3- Associate Professor of Reproductive Health, Department of Midwifery and Reproductive Health, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
4- Nursing and Midwifery Care Research Center, Non-Communicable Diseases Research Institute, Shahid Sadougi University of Medical Sciences, Yazd, Iran ,f.moshirenia@gmail.com
5- Pooyesh Fertility Center, Shahrak Salamat, Isfahan, Iran
6- MSc Student, School of Nutrition Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
2- Assistant Professor, Department of Public Health, Khoy University of Medical Sciences, Khoy, Iran
3- Associate Professor of Reproductive Health, Department of Midwifery and Reproductive Health, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
4- Nursing and Midwifery Care Research Center, Non-Communicable Diseases Research Institute, Shahid Sadougi University of Medical Sciences, Yazd, Iran ,
5- Pooyesh Fertility Center, Shahrak Salamat, Isfahan, Iran
6- MSc Student, School of Nutrition Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
Abstract: (444 Views)
Introduction: Natural supplements, such as royal jelly, are commonly used to improve health and well-being in the world and may be a successful treatment for damaged sperm exposed to environmental and chemical pathogens. Therefore, the present study was conducted with the aim of investigating the protective effects of royal jelly on sperm parameters using a narrative review method.
Methodology: The present study was conducted using a systematic review approach. A comprehensive search was conducted in various databases, including ISI, Web of Science, Cochrane, Pubmed, Google Scholar, ProQuest, and Ovid, as well as Persian databases, including ISC, SID, and Magiran, from January 2010 to March 2023. The research was carried out using Persian keywords: “Male infertility,” “Sperm parameters,” “Royal jelly,” “Protective effect,” “Fertility promotion,” and “Clinical trial” and their equivalent English keywords. The search results were 58 articles, of which 11 articles were reviewed according to the objectives of the study.
Findings: Royal jelly consumption is effective on sperm parameters and can improve sperm viability, number, and motility. It also has a protective effect on the negative effects of heat stress, nicotine consumption, exposure to lead compounds, and the use of drugs, such as bleomycin and hydroxyurea.
Conclusion: Royal jelly, as a protective agent, improves sperm viability, number, and motility and is effective at medium and high doses. However, very high or low doses have little effect, and further studies are needed to determine the optimal dose. Human clinical research is needed to determine the effects and appropriate dosage of royal jelly on male fertility with sperm disorders.
Methodology: The present study was conducted using a systematic review approach. A comprehensive search was conducted in various databases, including ISI, Web of Science, Cochrane, Pubmed, Google Scholar, ProQuest, and Ovid, as well as Persian databases, including ISC, SID, and Magiran, from January 2010 to March 2023. The research was carried out using Persian keywords: “Male infertility,” “Sperm parameters,” “Royal jelly,” “Protective effect,” “Fertility promotion,” and “Clinical trial” and their equivalent English keywords. The search results were 58 articles, of which 11 articles were reviewed according to the objectives of the study.
Findings: Royal jelly consumption is effective on sperm parameters and can improve sperm viability, number, and motility. It also has a protective effect on the negative effects of heat stress, nicotine consumption, exposure to lead compounds, and the use of drugs, such as bleomycin and hydroxyurea.
Conclusion: Royal jelly, as a protective agent, improves sperm viability, number, and motility and is effective at medium and high doses. However, very high or low doses have little effect, and further studies are needed to determine the optimal dose. Human clinical research is needed to determine the effects and appropriate dosage of royal jelly on male fertility with sperm disorders.
Type of Study: Review Article |
Subject:
Basic Sciences
Received: 2024/07/7 | Accepted: 2024/10/2 | Published: 2025/03/12
Received: 2024/07/7 | Accepted: 2024/10/2 | Published: 2025/03/12
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