Abstract Background & Objectives: Bacterial pneumonia occurs in most hospitalized patients and contributes the main leading cause of morbidity and mortality. We aimed to determine the incidence of pneumonia, isolate the bacterial agents of pneumonia and identification of risk factors for pneumonia. Material & Methods: This is a cross-sectional and descriptive study. From total number of542 patients hospitalized in the intensive care unit of Imam Reza Hospital due to various reasons, 78 patients with pneumonia and bacterial infections were selected. After identifying patients with nosocomial infection the required tests were done. The collected data were analyzed using the software INIS. Results: The incidence of nosocomial pneumonia was 14/4%, 38 (48/8%) were male and 40 (51/2%) were female. The mean age was 54/3 ± 26/2, 94/7% of patients with intubation, ventilator and suction was suffering from pneumonia. Also, 8/97% had a history of bronchitis and (28/1%) of asthma. The most frequent pathogens were Escherichi coli (26/15%), Pseudomonas aeruginosa (21/53%), Staphylococcus saprophytICUs (18.46%), Enterobacter spp. (15/38%), Klebsiella spp. (12/30%), Staphylococcus epidermidis (4/61%) and Streptococcus viridance (1/53%). Conclusions: Tracheal tube and mechanical ventilation increase risk of pneumonia. It is recommended, to avoid as much as possible any unnecessary interventions in intensive care unit and in case of mechanical ventilation, care and hygiene items must be taken to reduce the incidence of pneumonia
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