Abstract Background and objectives: spiritual well-being coordinate the dimensions of life together. Quality of life can be influenced by emotional - psychological and occupational factors. This study investigated the relationship between Spiritual Well-being and quality of life in nurses. Methods and Materials: This descriptive analytical research was conducted on 93 nurses at Hashemi Nejad Hospital in Mashhad. SF36 quality of life and SWBS Spiritual Well-being questionnaire were used. The collected data were analyzed in SPSS 15 using Chi-square, independent T Test, Fisher's exact test, pearson correlation coefficient, Stepwise multiple regression and logistic regression. Results: the mean age of under research Persons was 32/52 ± 7/2. Mean score of Quality of life and Spiritual Well-being were 64.38±17.84 and 94.3±16 . Multiple regression analysis showed that the Spiritual Well-being have a significantly association with quality of life. Logistic regression test showed that with 10 points to Spiritual Well-being, the odds ratio (OR) Good quality of life was 1/781. Conclusion: High level of Spiritual Well-being in under research nurses was associated with good quality of life.
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