Volume 15, Issue 4 (winter 2024)
2024, 15(4): 36-43 |
Back to browse issues page
Ethics code: IR.UMA.REC.1400.074
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Nabilpour M, Seifi F, Pour Rahim A. Comparison of Eight Weeks of Moderate-intensity Continuous Training (MICT) and High-intensity Intermittent Training (HIIT) with Sodium Citrate Supplementation on PGC-1α Expression. North Khorasan University of Medical Sciences 2024; 15 (4) :36-43
URL: http://journal.nkums.ac.ir/article-1-2867-en.html
URL: http://journal.nkums.ac.ir/article-1-2867-en.html
1- Ph.D. in Sports Physiology, Department of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
2- Associate Professor, Department of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran ,f.seify@yahoo.com
3- Associate Professor, Department of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
2- Associate Professor, Department of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran ,
3- Associate Professor, Department of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
Abstract: (1010 Views)
Introduction: Sports activity increases the expression of PGC-1α, the regulatory factor of mitochondrial biogenesis. This study aimed to investigate the effect of eight weeks of Moderate-intensity Continuous Training (MICT) and High-intensity Intermittent Training (HIIT), along with sodium citrate supplementation, on PGC-1α expression in male Wistar rats.
Method: Forty rats were placed in the following five groups: Control, MICT, MICT+sodium citrate, HIIT, and HIIT+sodium citrate. The continuous training group ran for eight weeks and five sessions per week with an average intensity of 70% of the maximum running speed for 15-30 minutes. The interval training group ran for 12 minutes with an intensity range of 50% and 90%. In addition to exercise, the exercise+supplement groups received 15 mmol/l sodium citrate supplement daily. The expression of PGC-1α in the soleus muscle was measured by the western blot method. Data analysis was done using one-way analysis of variance and Tukey's post hoc test.
Results: The PGC-1α protein expression increased in both the training groups and the training+supplement groups compared to the control group (P=0.001). Furthermore, adding sodium citrate could significantly increase the PGC-1α expression in the MICTgroup+supplement compared to the MICT group (P=0.005). However, the HIIT had a higher effect on PGC-1α expression than the MICT group.
Conclusion: Despite the effectiveness of both training methods, sodium citrate supplementation before HIIT could have more synergistic effects in increasing the expression of PGC-1α.
Method: Forty rats were placed in the following five groups: Control, MICT, MICT+sodium citrate, HIIT, and HIIT+sodium citrate. The continuous training group ran for eight weeks and five sessions per week with an average intensity of 70% of the maximum running speed for 15-30 minutes. The interval training group ran for 12 minutes with an intensity range of 50% and 90%. In addition to exercise, the exercise+supplement groups received 15 mmol/l sodium citrate supplement daily. The expression of PGC-1α in the soleus muscle was measured by the western blot method. Data analysis was done using one-way analysis of variance and Tukey's post hoc test.
Results: The PGC-1α protein expression increased in both the training groups and the training+supplement groups compared to the control group (P=0.001). Furthermore, adding sodium citrate could significantly increase the PGC-1α expression in the MICTgroup+supplement compared to the MICT group (P=0.005). However, the HIIT had a higher effect on PGC-1α expression than the MICT group.
Conclusion: Despite the effectiveness of both training methods, sodium citrate supplementation before HIIT could have more synergistic effects in increasing the expression of PGC-1α.
Keywords: High intensity interval training, Moderate intensity continuous training, Sodium citrate, PGC-1α
Type of Study: Orginal Research |
Subject:
Basic Sciences
Received: 2023/07/18 | Accepted: 2023/09/30 | Published: 2024/01/1
Received: 2023/07/18 | Accepted: 2023/09/30 | Published: 2024/01/1
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
